I don't know if this qualifies as a feature request or a case of caveat emptor, but I found a small bug that could severely aggrevate users trying 100 runs. I was doing a 100 run and was up to the NS tower. I don't have the right skills permed to get my familiars > 20lb. So via the built in kol tower script, it was leveling up the familiar I needed when the wormwood/semirare counter went up. And because whichever it was caused a combat without swapping out familiar, it ruined my 100 run.
tldr; request to heed is_100run variable when CC triggers an adventure.