The Mafia relay browser combat button for noodles is grayed out (disabled) if it's already been used that combat. This is almost always the correct behavior. However, this Spaghetti Demon (final form of the Pastamancer Nemesis) can have noodles cast on it multiple times. So against that opponent, that button should be clickable multiple times. As it stands right now (build 8499), the player instead has to use the pull-down skill menu.