i'm entirely happy to offer limited support for pathed runs. While supporting all runs would be good, the point of the script for me remains easy karma grinding - if someone wanted to play runs, they'd just play them.
I've started a muscle playthrough, unscripted. It seems that the script would probably do alright just ignoring safeMox() but probably best to do a Sauceror run as then you could just murder the crap out of everything and not have to worry, so long as you got init, which you probably would. I'd be fine with saying that moxie / muscle BIG! runs aren't well supported (for example).
[The above has the obvious caveat that if anyone fancies having a bash at making life easier for any particular path, go for it - that's the whole reason for the SVN!]